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SIENA

The SIENA (Steroids in Eosinophil Negative Asthma) study aims to find out if people should take an asthma controller medication based on the type of inflammatory cells (called eosinophils) present in their sputum. Taking part in this study includes 9 clinic visits and 8 phone calls over approximately 42 weeks. As part of the study, you would be taking an inhaled corticosteroid (ICS), which would be compared with the effect of placebo and with a long-acting muscarinic antagonist (LMA).

Your child may be eligible if he/she:
• Is 12-17 years old
• Has asthma


SIENA is a double blind, placebo controlled study. The study is being funded by the National Institutes of Health, via the National Heart, Lung and Blood Institute. The trail can be found on clinicaltrials.gov:

https://clinicaltrials.gov/ct2/show/NCT02066298