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Best African American Response to Asthma Drugs (BARD) Trial

The purpose of this study is to find the best asthma treatment to add for African American/Black children who have asthma that is not well controlled on a low dose of inhaled steroid. We are comparing four different treatments for asthma. If your child is enrolled in the study, they will stop taking their regular asthma medication and receive the four different study treatments in a random order. This study will also try to find out if African American/Black adults and children differ in how they respond to the medications used in this study.

The study is being funded by the National Institutes of Health, via the National Heart, Lung and Blood Institute. The trail can be found on clinicaltrials.gov:

https://clinicaltrials.gov/ct2/show/NCT01967173

If your child is enrolled in the study, they will stop taking their regular asthma medication and receive the four different study treatments in random order:

1. Combined low dose fluticasone plus salmeterol
2. Low dose fluticasone alone
3. Combined medium dose fluticasone plus salmeterol
4. Medium dose fluticasone alone

Your child may be eligible if he/she:
• is 5-17 years old
• has asthma symptoms despite asthma treatment.
• is of African American/Black ancestry (have at least one African American/Black grandparent)