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APRIL - Azithromycin for Preventing the development of upper Respiratory tract Illness into Lower respiratory tract symptoms

The APRIL study is looking at preventing coughing or wheezing symptoms in children when they have colds. This study is being conducted by Dr. Michael Cabana, Dr. Ngoc Ly and Dr. Shannon Thyne at UCSF and is funded by the National Institutes of Health and the National Heart, Lung and Blood Institutes. APRIL will see if giving a commonly prescribed antibiotic at the beginning of a cold will prevent symptoms from getting worse and developing into more severe symptoms like wheezing. Parents will identify their child’s first cold symptoms and start the APRIL treatment (either Azithromycin or a placebo given once daily for 5 days along with albuterol).